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For example, silver plays a competitive role in mitochondrial copper absorption, significantly inhibiting the uptake of copper by mitochondria and influencing the subsequent COX assembly process [277]

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observed significantly elevated expression levels of inflammatory cytokines IL-4, IL-6, IL-17A, IL-21, IL-22, and TNF-α in the vitreous cavity of patients with proliferative diabetic retinopathy (PDR) compared to the patients’ own serum concentrations and higher than the concentrations in the vitreous cavity of patients with epiretinal membranes or macular holes [151]